BRAIN CANCER

The Hassenfeld Children’s Hospital at NYU Langone and Perlmutter Cancer Center recently welcomed 2 new leaders in pediatric oncology, Elizabeth A. Raetz, MD, and Theodore P. Nicolaides, MD.

In a recent phase Ib study, the combination of carboxyamidotriazole orotate (CTO) and temozolomide (Temodar) produced positive safety and efficacy results in patients with glioblastoma (GBM) or anaplastic gliomas, with or without treatment with radiotherapy.

The use of personalized neoantigen vaccines demonstrated promising results in a recent phase I/Ib trial of patients with glioblastoma.

Rachel Grossman, MD, of Tel Aviv Sourasky Medical Center, discusses the treatment landscape for patients with newly diagnosed glioblastoma. She focuses on treatments utilizing tumor treating fields, an antimitotic treatment.