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An expert discusses how the IMpower133 trial established atezolizumab plus chemotherapy as standard care for extensive-stage small cell lung cancer (ES-SCLC), improving overall survival from 10.3 to 12.3 months, though most patients still don't achieve long-term survival.

An expert discusses the MARIPOSA study’s impact on managing central nervous system (CNS) involvement in EGFR-mutated non–small cell lung cancer, emphasizing improved brain progression-free survival, dual-targeted resistance prevention, and a promising shift toward more effective and personalized treatment strategies.