Opinion|Videos|September 17, 2024

Second-Line Strategies in cGVHD: Efficacy Data with Ruxolitinib

Author(s)Yi-Bin Chen, MD, Corey S. Cutler, MD, MPH, FRCPC, Sami Brake, MD

Panelists discuss how ruxolitinib has demonstrated efficacy as a second-line treatment strategy for chronic graft-versus-host disease, reviewing the available data on its effectiveness.

Episodes in this series

4 KOLs are featured in this series.

EP. 1 Chronic GVHD and Patient Quality of Life: Multisystem Effects and Functional Impairments

4 KOLs are featured in this series.

EP. 2 Multisystem cGVHD Manifestations: A Case Study with NIH Organ-Specific Scoring

4 KOLs are featured in this series.

EP. 3 Stratifying cGVHD Severity and Tailoring Therapy: Systemic Treatments and Supportive Care

4 KOLs are featured in this series.

EP. 4 Second-Line Strategies in cGVHD: Efficacy Data with Ruxolitinib

4 KOLs are featured in this series.

EP. 5 Navigating the Safety Profile of Ruxolitinib in cGVHD

4 KOLs are featured in this series.

EP. 6 Advancing to Third-Line Therapy: Belumosudil in cGVHD

4 KOLs are featured in this series.

EP. 7 Axatilimab in Refractory/Recurrent cGVHD: A Promising Later-Line Option

4 KOLs are featured in this series.

EP. 8 Clinical Considerations with Axtilimab in R/R GVHD

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Future Directions in cGVHD Treatment

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January 26th 2026

Later-Line and Combination Therapies in cGVHD and Future Directions

ByZachariah DeFilipp, MD

January 23rd 2026

Experts featured in this series.

Sequencing in the cGVHD Treatment Paradigm

ByLeyla O. Shune, MD

January 19th 2026

Second-Line Therapy and Ruxolitinib for cGVHD

ByZachariah DeFilipp, MD

January 16th 2026

Limitations of Steroids and Early Escalation in cGVHD Treatment

ByZachariah DeFilipp, MD

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