Opinion|Videos|March 11, 2025

Current Treatment Practices in Embolization-Eligible HCC

Author(s)Richard S. Finn, MD, Amit Singal, MD

Panelists discuss how systemic therapy plays a crucial role in embolization-eligible hepatocellular carcinoma (HCC), particularly for patients with progressive or extensive disease. In locally advanced cases, systemic therapies, including immunotherapy combinations and tyrosine kinase inhibitors (TKIs), are first-line options. Patients typically transition from transarterial chemoembolization (TACE) to systemic therapy upon progression, high tumor burden, or liver function decline.

Episodes in this series

2 experts in this video

EP. 1 Current Treatment Practices in Embolization-Eligible HCC

2 experts in this video

EP. 2 When to Move Beyond TACE: The Expanding Role of Systemic Therapy in Intermediate-Stage HCC

2 experts in this video

EP. 3 Navigating the Evolving First-Line Treatment Regimens in Intermediate-Stage HCC

2 experts in this video

EP. 4 Considerations for Treatment Approaches in Intermediate-Stage HCC

2 experts in this video

EP. 5 First-Line Therapy for Advanced HCC: The Role of TKIs and ICIs

2 experts in this video

EP. 6 Lenvatinib in Advanced HCC: Considerations for Monotherapy and Combination Regimens

2 experts in this video

EP. 7 Second-Line Therapy in Advanced HCC: Treatment Considerations and Evolving Options

2 experts in this video

EP. 8 The Evolving Role of Lenvatinib in the HCC Therapeutic Landscape

Video content above is prompted by the following:

Discuss the current role of systemic therapy in the embolization-eligible setting of HCC.
How are systemic therapies currently used in patients with locally advanced disease?
Is there a role for TKIs in first-line treatment?
In current clinical practice, when do patients typically transition from embolization-based therapies like TACE to systemic ones?

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