Opinion|Videos|May 6, 2024

Treatment Approaches for Myeloproliferative Neoplasms

This segment discusses the current classification of myeloproliferative neoplasms (MPNs) and the pathogenesis of these disorders, particularly the role of the JAK-STAT signaling pathway. It also presents a treatment algorithm for higher-risk myelofibrosis, with a focus on the use of JAK inhibitors such as ruxolitinib, fedratinib, pacritinib, and momelotinib.

Episodes in this series

EP. 1 Treatment Approaches for Myeloproliferative Neoplasms

EP. 1 Treatment Approaches for Myeloproliferative Neoplasms

EP. 2 Patient Case 1: Patient with Intermediate Risk Myelofibrosis

EP. 2 Patient Case 1: Patient with Intermediate Risk Myelofibrosis

EP. 3 Review of COMFORT I and COMFORT II Trials

EP. 3 Review of COMFORT I and COMFORT II Trials

EP. 4 Expert Takeaways from COMFORT I and II Trial Results

EP. 4 Expert Takeaways from COMFORT I and II Trial Results

EP. 5 Managing Treatment Strategy for Patient Who Previously Declined ASCT

EP. 5 Managing Treatment Strategy for Patient Who Previously Declined ASCT

EP. 6 Key Clinical Trials Highlighting JAK Inhibitors in Myelofibrosis Treatment

EP. 6 Key Clinical Trials Highlighting JAK Inhibitors in Myelofibrosis Treatment

EP. 7 Reviewing Impact of Emerging JAK Inhibitor Data

EP. 7 Reviewing Impact of Emerging JAK Inhibitor Data

EP. 8 Treatment of Advanced Polycythemia Vera

EP. 8 Treatment of Advanced Polycythemia Vera

EP. 9 Long-Term Outcomes with Ruxolitinib in Polycythemia Vera

EP. 9 Long-Term Outcomes with Ruxolitinib in Polycythemia Vera

EP. 10 PROUD-PV/CONTINUATION-PV Trials for Ropeginterferon Alfa-2b in Polycythemia Vera

EP. 10 PROUD-PV/CONTINUATION-PV Trials for Ropeginterferon Alfa-2b in Polycythemia Vera

EP. 11 MAJIC-PV Trial: Ruxolitinib vs Best Available Therapy in Hydroxyurea-Resistant/Intolerant Polycythemia Vera

EP. 11 MAJIC-PV Trial: Ruxolitinib vs Best Available Therapy in Hydroxyurea-Resistant/Intolerant Polycythemia Vera

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