Opinion|Videos|June 21, 2024

Navigating Later-Line Therapies for Progressive Urothelial Cancer

A key opinion leader delves into the intricacies of second-line and third-line treatment sequencing for patients with progressive disease, addressing the appropriate timing for repeat testing and elaborating on the critical factors that inform their personalized treatment approach.

  1. Briefly discuss second-line treatment options and rationale. Upon progression, what is your approach to management? Do you repeat testing at this point?
  2. Discuss the available third line and later treatment options. How do you discuss these options with patients?
  • What factors influence your decision to use sacituzumabgovitecan or enfortumab vedotin (e.g. comorbidities, prior treatment tolerance, biomarkers, metastasis site)?


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