Opinion|Videos|October 7, 2024

Navigating ICI Plus TKI Combinations for First-Line mRCC: Key Factors in Decision-Making

Author(s)Rana R. McKay, MD

Panelists discuss how they approach selecting among various immune checkpoint inhibitor (ICI) plus tyrosine kinase inhibitor (TKI) combinations for first-line treatment of metastatic renal cell carcinoma, considering key factors that influence their decision-making process and drawing insights from recent clinical trials such as CheckMate 9ER, KEYNOTE-426, and CLEAR.

Episodes in this series

1 KOL is featured in this series.

EP. 1 Evolving First-Line Treatment Strategies in Metastatic RCC: Key Factors Shaping Decision-Making

1 KOL is featured in this series.

EP. 2 Translating Clinical Data Into the Practice Setting: Monotherapy and Combination Therapies in Intermediate/Poor-Risk mRCC

1 KOL is featured in this series.

EP. 3 Navigating ICI Plus TKI Combinations for First-Line mRCC: Key Factors in Decision-Making

1 KOL is featured in this series.

EP. 4 Key Disease Characteristics Influencing the Choice Between ICI + TKI and ICI + ICI Regimens in mRCC

1 KOL is featured in this series.

EP. 5 Key Considerations for Adverse Event Management in mRCC: TKI Monotherapy vs ICI + TKI Combinations

1 KOL is featured in this series.

EP. 6 Impact of Adjuvant Immunotherapy on First-Line Treatment Decisions for Newly Diagnosed mRCC

1 KOL is featured in this series.

EP. 7 Balancing Efficacy Outcomes With Tolerability and Quality of Life in First-Line mRCC Treatment Decisions

1 KOL is featured in this series.

EP. 8 Unmet Needs and Future Perspective in the Frontline Management of mRCC

In your practice, how do you approach selection among the various immune checkpoint inhibitor plus tyrosine kinase inhibitor combinations for first-line treatment of metastatic renal cell carcinoma? What key factors influence your decision?
- CheckMate 9ER
- KEYNOTE-426
- CLEAR

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