Opinion|Videos|October 7, 2024

COMMANDS Study Update: Luspatercept vs. Epoetin Alfa in 1L Treatment

Author(s)Saeed Sadeghi, MD

Saeed Sadeghi, MD, discusses the updated data from the COMMANDS study presented at ASCO 2024, emphasizing the significance of outcome data comparing luspatercept to epoetin alfa in first-line (1L) treatment for lower-risk myelodysplastic syndromes (LR-MDS).

Episodes in this series

EP. 1 Mechanism of Action: Luspatercept vs Epoetin Alfa in LR-MDS

EP. 1 Mechanism of Action: Luspatercept vs Epoetin Alfa in LR-MDS

EP. 2 COMMANDS Study Update: Luspatercept vs. Epoetin Alfa in 1L Treatment

EP. 2 COMMANDS Study Update: Luspatercept vs. Epoetin Alfa in 1L Treatment

EP. 3 Real-World Data on Luspatercept in LR-MDS

EP. 3 Real-World Data on Luspatercept in LR-MDS

EP. 4 Health Care Resource Utilization: Luspatercept vs ESAs in MDS

EP. 4 Health Care Resource Utilization: Luspatercept vs ESAs in MDS

EP. 5 Current Approach to Treating Anemia in LR-MDS

EP. 5 Current Approach to Treating Anemia in LR-MDS

EP. 6 Future Perspective on Anemia Treatment in LR-MDS

EP. 6 Future Perspective on Anemia Treatment in LR-MDS

Video content above is prompted by the following:

Please discuss the updated data from the COMMANDS study presented at ASCO 2024.

What is the importance of the outcome data for luspatercept vs epoetin alfa in 1L treatment? (Zeidan et al,
J Clin Oncol. 2024; 42(suppl 16): 6565); (Della Porta et al, Lancet Haematol. 2024; 11:e646-658.)

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