Novel Therapies for <em>T315I</em>-Mutant CMLByOmar Al Ustwani, MDPublished: September 4th 2013 | Updated: April 18th 2020The use of tyrosine kinase inhibitors (TKIs) to inhibit BCR-ABL protein in chronic myeloid leukemia (CML) is one of the major milestones in modern oncology.