|Articles|July 29, 2013
Mechanism of Action: Afatinib (BIBW 2992)
Afatinib is an FDA-approved pan-HER inhibitor for the first-line treatment of patients with metastatic NSCLC whose tumors have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations.
Afatinib (Gilotrif), previously known as BIBW 2992, is an FDA-approved pan-HER inhibitor for the first-line treatment of patients with metastatic non-small cell lung cancer whose tumors have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test.
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